GAPDH Antibody, Biotin conjugated

Rare Species
Code CSB-PA009232HD01CH
Size US$166
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Product Details

Full Product Name
Rabbit anti-Chicken GAPDH Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
GAPDH antibody; GAPD antibody; Glyceraldehyde-3-phosphate dehydrogenase antibody; GAPDH antibody; EC 1.2.1.12 antibody; Peptidyl-cysteine S-nitrosylase GAPDH antibody; EC 2.6.99.- antibody
Raised in
Rabbit
Species Reactivity
Chicken
Immunogen
Recombinant Chicken Glyceraldehyde-3-phosphate dehydrogenase protein (2-333AA)
Immunogen Species
Chicken
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
Gene References into Functions
  1. Results show that despite being commonly used housekeeping genes neither GAPDH mRNA nor beta-actin mRNA is expressed in all cell types or tissues at high levels. Strikingly, expression levels are very low in some organs. PMID: 23099774
Subcellular Location
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus.
Protein Families
Glyceraldehyde-3-phosphate dehydrogenase family
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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